quasar

quasar is a C++ program for performing quantitative trait loci (QTL) mapping.

The program has the following features:

• ability to handle quantatative and count input data
• supports the PLINK bed/bim/fam genotype data format
• implements a fast variance-ratio approximation for mixed models
• implements Cox-Reid adjusted profile likelihood estimation for NB dispersion

Citation

Flexible and efficient count-distribution and mixed-model methods for eQTL mapping with quasar Jeffrey M. Pullin, Chris Wallace medRxiv 2025.07.17.25331702; doi: https://doi.org/10.1101/2025.07.17.25331702

Contact

quasar is under active developement and we appreciate your feedback, questions and feature requests. Contact: Jeffrey Pullin (jp2045[at]cam.ac.uk).

If you wish to submit an issue please do so on quasar's GitHub repository.

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